Article
Mutations of the EGFR, K-ras, EML4-ALK, and BRAF genes in resected pathological stage I lung adenocarcinoma.
Surgery today - 1 Sept 2016
Ohba Taro, Toyokawa Gouji, Osoegawa Atsushi, Hirai Fumihiko, Yamaguchi Masafumi, Taguchi Ken-Ichi, Seto Takashi, Takenoyama Mitsuhiro, Ichinose Yukito, Sugio Kenji
Abstract excerpt
BACKGROUND AND PURPOSE: The EGFR, K-ras, EML4-ALK, and BRAF genes are oncogenic drivers of lung adenocarcinoma. We conducted this study to analyze the mutations of these genes in stage I adenocarcinoma. METHODS: The subjects of this retrospective study were 256 patients with resected stage I lung adenocarcinoma. We analyzed mutations of the EGFR, K-ras, and BRAF genes, and the EML4-ALK fusion gene. We also...
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