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Article

The relationship between phenotype, ribotype, and clinical disease in human Clostridium difficile isolates.

Anaerobe - 1 Dec 2013

Carlson Paul E, Walk Seth T, Bourgis Alexandra E T, Liu Melissa W, Kopliku Fatos, Lo Eugene, Young Vincent B, Aronoff David M, Hanna Philip C

Abstract excerpt

Since 2000, Clostridium difficile isolates of ribotype 027 have been linked to outbreaks in North America and Europe and also an increased rate of colectomy and death among infected individuals. It has been proposed that enhanced sporulation and toxin production were associated with this apparent increase in virulence of 027 isolates. Since only a limited number of isolates have been examined, the relationship of...

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Identifiers

PMID: 23608205
DOI: 10.1016/j.anaerobe.2013.04.003
PMCID: PMC4038106

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