Article
The genetic diversity of Helicobacter pylori virulence genes is not associated with gastric atrophy progression.
Acta medica Okayama - 1 Jan 2013
Kita Masahide, Yokota Kenji, Okada Hiroyuki, Take Susumu, Takenaka Ryuta, Kawahara Yoshiro, Oguma Keiji, Matsushita Osamu, Yamamoto Kazuhide
Abstract excerpt
Atrophy of the gastric mucosa is a precursor of intestinal-type gastric cancer, and Helicobacter pylori infection causes atrophic gastritis. The aim of this study was to determine whether the genetic diversity of H. pylori virulence genes is associated with the development and progression of gastric atrophy in humans. We isolated and cultured H. pylori strains from patients with gastric ulcer and duodenal ulcer...
Topics
- Adhesins, Bacterial
- Antigens, Bacterial
- Atrophy
- Bacterial Proteins
- Disease Progression
- Duodenal Ulcer
- Female
- Gastritis
- Genetic Variation
- Helicobacter Infections