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Article

Long-lasting complete regression of established mouse tumors by counteracting Th2 inflammation.

Journal of immunotherapy (Hagerstown, Md. : 1997) - 1 May 2013

Dai Min, Wei Huafeng, Yip Yuen Yee, Feng Qinghua, He Kecheng, Popov Viorica, Hellstrom Ingegerd, Hellstrom Karl Erik

Abstract excerpt

Mice with intraperitoneal ID8 ovarian carcinoma or subcutaneous SW1 melanoma were injected with monoclonal antibodies (mAbs) to CD137PD-1CTLA4 7-15 days after tumor initiation. Survival of mice with ID8 tumors tripled and >40% of mice with SW1 tumors remained healthy >150 days after last treatment and are probably cured. Therapeutic efficacy was associated with a systemic immune response with memory and antigen...

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Share to Antigens, CD19
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23603859
DOI: 10.1097/CJI.0b013e3182943549
PMCID: PMC3685275

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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