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Article

Systems mapping of metabolic genes through control theory.

Advanced drug delivery reviews - 30 Jun 2013

Liu Guodong, Kong Lan, Wang Zhong, Wang Chenguang, Wu Rongling

Abstract excerpt

The formation of any complex phenotype involves a web of metabolic pathways in which one chemical is transformed through the catalysis of enzymes into another. Traditional approaches for mapping quantitative trait loci (QTLs) are based on a direct association analysis between DNA marker genotypes and end-point phenotypes, neglecting the mechanistic processes of how a phenotype is formed biochemically. Here, we...

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PMID: 23603209
DOI: 10.1016/j.addr.2013.04.007
PMCID: PMC4233129

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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