Article
Using volcano plots and regularized-chi statistics in genetic association studies.
Computational biology and chemistry - 1 Feb 2014
Li Wentian, Freudenberg Jan, Suh Young Ju, Yang Yaning
Abstract excerpt
Labor intensive experiments are typically required to identify the causal disease variants from a list of disease associated variants in the genome. For designing such experiments, candidate variants are ranked by their strength of genetic association with the disease. However, the two commonly used measures of genetic association, the odds-ratio (OR) and p-value may rank variants in different order. To integrate...
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