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Optimizing Gene Selection and Network-Level Insights in Hypertrophic Cardiomyopathy: A Novel Genetic Algorithm Combined with WGCNA and Statistical Filtering

2025-07-02

Abstract excerpt

A cardiac condition known as hypertrophic cardiomyopathy (HCM) is characterized by an irregular thickening of the heart muscle. There is still much to learn about its molecular mechanics. In order to pinpoint important genes and regulatory abnormalities in HCM, this work offers a thorough computational analysis of gene expression data. Two strategies are employed here. Initially, hub genes were identified, co-expr...

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Literature Corpus work
0032780e-33cc-5e91-9dc2-a9608cf7ccd1
DOI
10.1101/2025.07.01.25330641
Open publication

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Optimizing Gene Selection and Network-Level Insights in Hypertrophic Cardiomyopathy: A Novel Genetic Algorithm Combined with WGCNA and Statistical FilteringDOI 10.1101/2025.07.01.25330641
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