Article
Analysis and design of RNA sequencing experiments for identifying RNA editing and other single-nucleotide variants.
RNA (New York, N.Y.) - 1 Jun 2013
Lee Jae-Hyung, Ang Jason K, Xiao Xinshu
Abstract excerpt
RNA-sequencing (RNA-Seq) technologies hold enormous promise for novel discoveries in genomics and transcriptomics. In the past year, a surge of reports has analyzed RNA-Seq data to gain a global view of the RNA editome. Opposing results have been presented, giving rise to extensive debate surrounding one of the first such studies in which a daunting list of all 12 types of RNA-DNA differences (RDDs) were...
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