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Article

Genome-wide association study identifies GPC5 as a novel genetic locus protective against sudden cardiac arrest.

PloS one - 25 Mar 2010

Arking Dan E, Reinier Kyndaron, Post Wendy, Jui Jonathan, Hilton Gina, O'Connor Ashley, Prineas Ronald J, Boerwinkle Eric, Psaty Bruce M, Tomaselli Gordon F, Rea Thomas, Sotoodehnia Nona, Siscovick David S, Burke Gregory L, Marban Eduardo, Spooner Peter M, Chakravarti Aravinda, Chugh Sumeet S

Abstract excerpt

BACKGROUND: Existing studies indicate a significant genetic component for sudden cardiac arrest (SCA) and genome-wide association studies (GWAS) provide an unbiased approach for identification of novel genes. We performed a GWAS to identify genetic determinants of SCA. METHODOLOGY/PRINCIPAL FINDI...

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Source

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Identifiers

PMID: 20360844
DOI: 10.1371/journal.pone.0009879
PMCID: PMC2845611

Genes

GPC5
CAD
CSMD2
LIN9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20360844-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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