Article
Adiponectin G276T gene polymorphism is associated with cardiovascular disease in Japanese patients with type 2 diabetes.
Atherosclerosis - 1 Feb 2012
Katakami Naoto, Kaneto Hideaki, Matsuoka Taka-aki, Takahara Mitsuyoshi, Maeda Norikazu, Shimizu Ikki, Ohno Keizo, Osonoi Takeshi, Kawai Koichi, Ishibashi Fukashi, Imamura Kenichi, Kashiwagi Atsunori, Kawamori Ryuzo, Matsuhisa Munehide, Funahashi Tohru, Yamasaki Yoshimitsu, Shimomura Iichiro
Abstract excerpt
OBJECTIVE: Adiponectin has anti-atherogenic properties and reduced serum adiponectin levels are associated with cardiovascular disease (CVD). In this study, we examined the relationship between CVD and adiponectin (ADIPOQ) gene G276T polymorphism that is associated with serum adiponectin level in a large cohort of type 2 diabetic patients. RESEARCH DESIGN AND METHODS: We enrolled 2637 Japanese type 2 diabetic...
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