Article
Genetic variability on adiponectin gene affects myocardial infarction risk: the role of endothelial dysfunction.
International journal of cardiology - 20 Sept 2013
Antonopoulos Alexios S, Tousoulis Dimitris, Antoniades Charalambos, Miliou Antigoni, Hatzis George, Papageorgiou Nikolaos, Demosthenous Michalis, Tentolouris Constantinos, Stefanadis Christodoulos
Abstract excerpt
BACKGROUND: Adiponectin is an adipokine with an important role in cardiovascular system conferring anti-inflammatory and anti-atherogenic effects. Two common single nucleotide polymorphisms (SNP) on adiponectin gene, rs2241766 and rs1501299, have been associated with insulin resistance and diabetes mellitus risk however their effects on cardiovascular risk remain unclear. We examined the impact of rs2241766 and...
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