Adiponectin I164T mutation is associated with the metabolic syndrome and coronary artery disease.

doi:10.1016/j.jacc.2003.10.049

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Article

Adiponectin I164T mutation is associated with the metabolic syndrome and coronary artery disease.

Journal of the American College of Cardiology - 7 Apr 2004

Ohashi Koji, Ouchi Noriyuki, Kihara Shinji, Funahashi Tohru, Nakamura Tadashi, Sumitsuji Satoru, Kawamoto Toshiharu, Matsumoto Satoru, Nagaretani Hiroyuki, Kumada Masahiro, Okamoto Yoshihisa, Nishizawa Hitoshi, Kishida Ken, Maeda Norikazu, Hiraoka Hisatoyo, Iwashima Yoshio, Ishikawa Kazuhiko, Ohishi Mitsuru, Katsuya Tomohiro, Rakugi Hiromi, Ogihara Toshio, Matsuzawa Yuji

Abstract excerpt

OBJECTIVES: This study examined the association of mutations in adiponectin gene with the prevalence of coronary artery disease (CAD). BACKGROUND: Coronary artery disease is a major cause of mortality in the industrial countries. Adiponectin gene locus, chromosome 3q27, is the candidate site for CAD. We have reported that adiponectin has antiatherogenic and antidiabetic properties, and that the plasma levels...

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PMID: 15063429
DOI: 10.1016/j.jacc.2003.10.049

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