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Cognitive function, plasma MnSOD activity, and MnSOD Ala-9Val polymorphism in patients with schizophrenia and normal controls.

Schizophrenia bulletin - 1 May 2014

Zhang Xiang Y, Chen Da C, Xiu Mei H, Yang Fu D, Tan Yunlong, Luo Xingguang, Zuo Lingjun, Kosten Therese A, Kosten Thomas R

Abstract excerpt

Excessive reactive oxygen species are thought to produce oxidative damage that underlies neurodegeneration and cognitive impairment in several disorders including schizophrenia. The functional Ala-9Val polymorphism of the mitochondrial enzyme manganese superoxide dismutase (MnSOD), which detoxifies superoxide radicals to hydrogen peroxide, has been associated with schizophrenia. However, no study has reported its...

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Identifiers

PMID: 23588476
DOI: 10.1093/schbul/sbt045
PMCID: PMC3984504

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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