Article
A Molecular and Cellular Context-Dependent Role for Ir76b in Detection of Amino Acid Taste.
Cell reports - 17 Jan 2017
Ganguly Anindya, Pang Lisa, Duong Vi-Khoi, Lee Angelina, Schoniger Hanni, Varady Erika, Dahanukar Anupama
Abstract excerpt
Amino acid taste is expected to be a universal property among animals. Although sweet, bitter, salt, and water tastes have been well characterized in insects, the mechanisms underlying amino acid taste remain elusive. From a Drosophila RNAi screen, we identify an ionotropic receptor, Ir76b, as necessary for yeast preference. Using calcium imaging, we identify Ir76b+ amino acid taste neurons in legs, overlapping...
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