Article
Association of TCF7L2 gene polymorphisms with T2DM in the population of Hyderabad, India.
PloS one - 1 Jan 2013
Uma Jyothi Kommoju, Jayaraj Maruda, Subburaj Kadarkarai Samy, Prasad Kotla Jaya, Kumuda Irgam, Lakshmi Velaga, Reddy Battini Mohan
Abstract excerpt
We attempt to evaluate the nature of association of TCF7L2 gene variants with T2DM, for the first time in the population of Hyderabad, which is considered to be diabetic capital of India. It is a case-control study of the three SNPs of TCF7L2, rs7903146, rs12255372 and rs11196205, genotyped on Sequenom Massarray platform, in a sample of 758 patients and 621 controls. The risk allele frequency of the three SNPs...
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