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Antagonistic self-sensing and mate-sensing signaling controls antibiotic-resistance transfer

8 Apr 2013

Abstract excerpt

Conjugation is one of the most common ways bacteria acquire antibiotic resistance, contributing to the emergence of multidrug-resistant "superbugs." Bacteria of the genus Enterococcus faecalis are highly antibiotic-resistant nosocomial pathogens that use the mechanism of conjugation to spread antibiotic resistance between resistance-bearing donor cells and resistance-deficient recipient cells. Here, we report a...

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PMID: 23569272
DOI: 10.1073/pnas.1212256110

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