Article
The endothelial nitric oxide synthase T-786c mutation, a treatable etiology of Prinzmetal's angina.
Translational research : the journal of laboratory and clinical medicine - 1 Jul 2013
Glueck Charles J, Valdes Alejandro, Bowe Dedrick, Munsif Siddharth, Wang Ping
Abstract excerpt
We assessed to what degree the endothelial nitric oxide synthase (eNOS) T-786C polymorphism, leading to reduced nitric oxide (NO) production-coronary artery spasm, was reversibly associated with Prinzmetal's variant angina (PVA). ENOS T-786C PCR analyses were done in 19 women, 8 men, 26 Caucasian, 1 African-American, median age 53, with well-documented PVA and in 72 healthy controls who did not differ by race or...
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