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Article

Association study between of Tie2/angiopoietin-2 and VEGF/KDR pathway gene polymorphisms and vascular malformations.

Gene - 10 Jul 2013

Zheng Qiupeng, Du Jing, Zhang Zhaofeng, Xu Jianhua, Fu Lingyuan, Cao Yunlei, Huang Xianliang, Guo Lingli

Abstract excerpt

Vascular malformations (VMs) are common congenital and neonatal dysmorphogenesis. VMs mostly occur sporadically with a few exceptions of inheritability. Tie2/angiopoietins-2 (Ang-2) and VEGF/KDR pathways are known to be involved in normal and pathogenic angiogenesis. Our study was aimed to test the contribution of these pathway gene variants to VMs. A total of 8 variants were found among 103 VM patients and 142...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Receptor, TIE-2

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Share to Vascular Endothelial Growth Factor Receptor-2

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Source

Identifiers

PMID: 23566851
DOI: 10.1016/j.gene.2013.02.053

Genes

KDR
ANTXR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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