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Article

Strong expression of survivin is associated with positive response to radiotherapy and improved overall survival in head and neck squamous cell carcinoma patients.

International journal of cancer - 15 Oct 2013

Farnebo Lovisa, Tiefenböck Katharina, Ansell Anna, Thunell Lena K, Garvin Stina, Roberg Karin

Abstract excerpt

Head and neck squamous cell carcinoma (HNSCC) is a malignancy that is associated with severe mortality despite advances in therapy. Today's standard treatment most commonly includes radiotherapy, often combined with chemotherapy or surgery. There are so far no established biomarkers to predict response to radiation, and thus the aim of this study was to investigate a series of markers that could potentially...

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Topics

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Share to Carcinoma, Squamous Cell
Share to Down-Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Head and Neck Neoplasms

Share to Inhibitor of Apoptosis Proteins

Share to Receptor, Fibroblast Growth Factor, Type 4

Share to RNA, Small Interfering

Share to Survivin

Share to Xeroderma Pigmentosum Group D Protein

Source

Identifiers

PMID: 23564498
DOI: 10.1002/ijc.28200

Genes

FGFR4
MDM2
XPC
XRCC1
XRCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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