Article
Hybrid cluster proteins and flavodiiron proteins afford protection to Desulfovibrio vulgaris upon macrophage infection.
Journal of bacteriology - 1 Jun 2013
Figueiredo Mafalda C O, Lobo Susana A L, Sousa Sara H, Pereira Fábio P, Wall Judy D, Nobre Lígia S, Saraiva Lígia M
Abstract excerpt
Desulfovibrio species are Gram-negative anaerobic sulfate-reducing bacteria that colonize the human gut. Recently, Desulfovibrio spp. have been implicated in gastrointestinal diseases and shown to stimulate the epithelial immune response, leading to increased production of inflammatory cytokines by macrophages. Activated macrophages are key cells of the immune system that impose nitrosative stress during...
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