Desulfovibrio vulgaris exacerbates sepsis by inducing inflammation and oxidative stress in multiple organs

Abstract excerpt

Introduction Sepsis is a life-threatening condition that often leads to organ dysfunction and systemic inflammation, with gut microbiota dysbiosis playing a crucial role in its pathogenesis. The role of Desulfovibrio vulgaris (D. vulgaris), a potentially pathogenic bacterium, in sepsis remains unclear. Methods We first assessed the abundance of D. vulgaris in the feces of septic mice and patients using qPCR. Mice...

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