Article
The CMYA5 gene confers risk for both schizophrenia and major depressive disorder in the Han Chinese population.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Sept 2014
Wang Qingzhong, He Kuanjun, Li Zhiqiang, Chen Jianhua, Li Wenjin, Wen Zujia, Shen Jiawei, Qiang Yu, Ji Jue, Wang Yujiong, Shi Yongyong
Abstract excerpt
OBJECTIVES: A recent genome-wide association study (GWAS) of the European population implicated the CMYA5 gene in schizophrenia. Previous functional studies showed that the CMYA5 protein can interact with DTNBP1 and PKA, providing further support for a role of CMYA5 in the pathogenesis of schizophrenia. However, this association requires additional validation in independent populations. METHODS: To validate the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
