Article
Association of ketone body levels with hyperglycemia and type 2 diabetes in 9,398 Finnish men.
Diabetes - 1 Oct 2013
Mahendran Yuvaraj, Vangipurapu Jagadish, Cederberg Henna, Stancáková Alena, Pihlajamäki Jussi, Soininen Pasi, Kangas Antti J, Paananen Jussi, Civelek Mete, Saleem Niyas K, Pajukanta Päivi, Lusis Aldons J, Bonnycastle Lori L, Morken Mario A, Collins Francis S, Mohlke Karen L, Boehnke Michael, Ala-Korpela Mika, Kuusisto Johanna, Laakso Markku
Abstract excerpt
We investigated the association of the levels of ketone bodies (KBs) with hyperglycemia and with 62 genetic risk variants regulating glucose levels or type 2 diabetes in the population-based Metabolic Syndrome in Men (METSIM) study, including 9,398 Finnish men without diabetes or newly diagnosed type 2 diabetes. Increasing fasting and 2-h plasma glucose levels were associated with elevated levels of acetoacetate...
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