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Article

Matrix metalloproteinase-9 promoter polymorphism associated with upper lung dominant emphysema.

American journal of respiratory and critical care medicine - 1 Dec 2005

Ito Isao, Nagai Sonoko, Handa Tomohiro, Muro Shigeo, Hirai Toyohiro, Tsukino Mitsuhiro, Mishima Michiaki

Abstract excerpt

RATIONALE: Matrix metalloproteinase 9 (MMP-9) has proteolytic activity against connective tissue proteins and appears to play an important role in the development of chronic obstructive pulmonary disease (COPD). The functional polymorphism of MMP-9 (C-1562T) is considered as one of the candidate genes in the susceptibility to COPD. OBJECTIVES: To determine if MMP-9 (C-1562T) is related to the development of COPD...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Tomography, X-Ray Computed

Source

Identifiers

PMID: 16126934
DOI: 10.1164/rccm.200506-953OC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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