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Article

Fine characterisation of a recombination hotspot at the DPY19L2 locus and resolution of the paradoxical excess of duplications over deletions in the general population.

PLoS genetics - 1 Mar 2013

Coutton Charles, Abada Farid, Karaouzene Thomas, Sanlaville Damien, Satre Véronique, Lunardi Joël, Jouk Pierre-Simon, Arnoult Christophe, Thierry-Mieg Nicolas, Ray Pierre F

Abstract excerpt

We demonstrated previously that 75% of infertile men with round, acrosomeless spermatozoa (globozoospermia) had a homozygous 200-Kb deletion removing the totality of DPY19L2. We showed that this deletion occurred by Non-Allelic Homologous Recombination (NAHR) between two homologous 28-Kb Low Copy...

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Source

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Identifiers

PMID: 23555282
DOI: 10.1371/journal.pgen.1003363
PMCID: PMC3605140

Genes

PRDM9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23555282-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Fine characterisation of a recombination hotspot at the DPY19L2 locus and resolution of the paradoxical excess of duplications over deletions in the general population.PMID 23555282Read ↗

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