Article
Commonality in Down and fetal alcohol syndromes.
Birth defects research. Part A, Clinical and molecular teratology - 1 Apr 2013
Solzak Jeffrey P, Liang Yun, Zhou Feng C, Roper Randall J
Abstract excerpt
BACKGROUND: Down syndrome (DS) and Fetal Alcohol Syndrome (FAS) are two leading causes of birth defects with phenotypes ranging from craniofacial abnormalities to cognitive impairment. Despite different origins, we report that in addition to sharing many phenotypes, DS and FAS may have common underlying mechanisms of development. METHODS: Literature was surveyed for DS and FAS as well as mouse models. Gene...
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