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Article

Crystallographic analysis of the ENTH domain from yeast epsin Ent2 that induces a cell division phenotype.

Protein science : a publication of the Protein Society - 1 Jun 2013

Costakes Gregory T, Sen Arpita, Aguilar R Claudio, Stauffacher Cynthia V

Abstract excerpt

Epsins are eukaryotic, endocytic adaptor proteins primarily involved in the early steps of clathrin mediated endocytosis. Two epsins exist in Saccharomyces cerevisiae, Ent1 and Ent2, with single epsin knockouts being viable, while the double knockout is not. These proteins contain a highly conserved Epsin N-terminal homology (ENTH) domain that is essential for cell viability. In addition, overexpression of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23553749
DOI: 10.1002/pro.2259
PMCID: PMC3690715

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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