Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ribonucleotide reductase expression in cervical cancer: a radiation therapy oncology group translational science analysis.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 May 2013

Kunos Charles A, Winter Kathryn, Dicker Adam P, Small William, Abdul-Karim Fadi W, Dawson Dawn, Jhingran Anuja, Valicenti Richard, Weidhaas Joanne B, Gaffney David K

Abstract excerpt

OBJECTIVE: To evaluate pretherapy ribonucleotide reductase (RNR) expression and its effect on radiochemotherapeutic outcome in women with cervical cancer. METHODS/MATERIALS: Pretherapy RNR M1, M2, and M2b immunohistochemistry was done on cervical cancer specimens retrieved from women treated on Radiation Therapy Oncology Group (RTOG) 0116 and 0128 clinical trials. Enrollees of RTOG 0116 (node-positive stages...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Clinical Trials, Phase II as Topic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Disease-Free Survival

Share to Ribonucleotide Reductases

Share to Translational Research, Biomedical

Share to Treatment Outcome

Share to United States

Share to Uterine Cervical Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 23552804
DOI: 10.1097/IGC.0b013e31828b4eb5
PMCID: PMC3662019

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ribonucleotide reductase expression in cervical cancer: a radiation therapy oncology group translational science analysis.PMID 23552804Read ↗

Downregulation of ribonucleotide reductase subunits M2 induces apoptosis and G1 arrest of cervical cancer cellsSemantic proximity Read ↗

Adjuvant treatment in early-stage endometrial cancer: context-dependent impact of somatic CTNNB1 mutation on recurrence-free survival.Semantic proximity Read ↗

HNF1α Contributes to Radio-Resistance in Cervical Cancer Via Regulating the CircHNF1α/miR-204-3p/RAD51D Regulatory AxisSemantic proximity Read ↗

Role of estrogen receptor alpha in human cervical cancer-associated fibroblasts: a transcriptomic studySemantic proximity Read ↗

Using the Radiosensitivity Index (RSI) to Predict Pelvic Failure in Endometrial Cancer Treated With Adjuvant Radiation Therapy.Semantic proximity Read ↗

Ribonucleotide Reductase Inhibition Enhances Chemoradiosensitivity of Human Cervical CancersSemantic proximity Read ↗

Investigation of Radiosensitivity Gene Signatures in Cancer Cell LinesSemantic proximity Read ↗

Hypoxia-Induced Gene Expression in Chemoradioresistant Cervical Cancer Revealed by Dynamic Contrast-Enhanced MRISemantic proximity Read ↗

RhoC regulates radioresistance via crosstalk of ROCK2 with the DNA repair machinery in cervical cancerSemantic proximity Read ↗

Hemoglobin level in cervical cancer: a surrogate for an infiltrative phenotype.Semantic proximity Read ↗

Poor prognosis associated with human papillomavirus α7 genotypes in cervical carcinoma cannot be explained by intrinsic radiosensitivity.Semantic proximity Read ↗

Regulatory effects of COL1A1 on apoptosis induced by radiation in cervical cancer cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.