Article
The effect of genetic admixture in an association study: genetic polymorphisms and chromosome aberrations in a Colombian population exposed to organic solvents.
Annals of human genetics - 1 Jul 2013
Hoyos-Giraldo Luz Stella, Escobar-Hoyos Luisa F, Reyes-Carvajal Ingrid, García Jharley J, Córdoba Liliana, Gómez Adalberto Sánchez, García-Vallejo Felipe, Cajas-Salazar Nohelia, Carvajal Silvio, Bedoya Gabriel
Abstract excerpt
The human population is heterogeneous in genetic susceptibility, chromosomal instability and disease risk; all factors which depend on inherited genetic constitution and acquired nongenetic environmental and occupational factors. Recently, special attention has been directed to the identification of sources of potential bias in population studies of gene-environment interactions including genetic admixture. The...
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