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Comparative Genomics of Serial Isolates of <i>Cryptococcus neoformans</i> Reveals Gene Associated With Carbon Utilization and Virulence

28 Mar 2013

Abstract excerpt

The opportunistic fungal pathogen Cryptococcus neoformans is a leading cause of mortality among the human immunodeficiency virus/acquired immunodeficiency syndrome population and is known for frequently causing life-threatening relapses. To investigate the potential contribution of in-host microevolution to persistence and relapse, we have analyzed two serial isolates obtained from a patient with acquired...

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PMID: 23550133
DOI: 10.1534/g3.113.005660

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