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A Unique Chromosomal Rearrangement in the Cryptococcus neoformans var. <i>grubii</i> Type Strain Enhances Key Phenotypes Associated with Virulence

28 Feb 2012

Abstract excerpt

UNLABELLED: The accumulation of genomic structural variation between closely related populations over time can lead to reproductive isolation and speciation. The fungal pathogen Cryptococcus is thought to have recently diversified, forming a species complex containing members with distinct morphologies, distributions, and pathologies of infection. We have investigated structural changes in genomic architecture...

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PMID: 22375073
DOI: 10.1128/mbio.00310-11

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