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Article

Relationship between SRD5A2 rs9282858 polymorphism and the susceptibility of prostate cancer: A meta-analysis based on 20 publications.

Medicine - 1 May 2017

Fang Cheng, Guo Zhong-Qiang, Chen Xiao-Yan, Liu Tong-Zu, Zeng Xian-Tao, Wang Xing-Huan

Abstract excerpt

The pathogenetic mechanism of prostate cancer (PCa) has not been understood completely, and gene polymorphisms have been demonstrated to play a critical role in the course. It has been reported that rs9282858 polymorphism of steroid 5-α-reductase type 2 (SRD5A2) may affect the susceptibility of PCa, but some researches showed different results. We therefore carried out a meta-analysis to clarify this...

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3-Oxo-5-alpha-Steroid 4-Dehydrogenase
Genetic Predisposition to Disease
Membrane Proteins
Observational Studies as Topic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Prostatic Neoplasms

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Identifiers

PMID: 28489754
DOI: 10.1097/MD.0000000000006791
PMCID: PMC5428588

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