Article
A Dopamine Pathway Gene Risk Score for Cognitive Recovery Following Traumatic Brain Injury: Methodological Considerations, Preliminary Findings, and Interactions With Sex.
The Journal of head trauma rehabilitation - 1 Jan 2000
Myrga John M, Failla Michelle D, Ricker Joseph H, Dixon C Edward, Conley Yvette P, Arenth Patricia M, Wagner Amy K
Abstract excerpt
OBJECTIVES: With evidence of sexual dimorphism involving the dopamine (DA)-pathway, and the importance of DA pathways in traumatic brain injury (TBI) recovery, we hypothesized that sex × DA-gene interactions may influence cognition post-TBI. PARTICIPANTS: Adult survivors of severe TBI (n = 193) consecutively recruited from a level 1 trauma center. DESIGN: Risk allele assignments were made for multiple DA pathway...
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