Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The VPS35 gene and Parkinson's disease.

Movement disorders : official journal of the Movement Disorder Society - 1 May 2013

Deng Hao, Gao Kai, Jankovic Joseph

Abstract excerpt

Parkinson's disease (PD), the second most common age-related neurodegenerative disease, is characterized by loss of dopaminergic and nondopaminergic neurons, leading to a variety of motor and nonmotor symptoms. In addition to environmental factors, genetic predisposition and specific gene mutations have been shown to play an important role in the pathogenesis of this disorder. Recently, the identification of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to VPS35 gene
Share to Genetic Predisposition to Disease
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neurological diseases and metabolism

Share to Parkinson Disease

Share to Parkinson's Disease Mechanisms and Treatments

Share to Transcription Factors

Share to Vesicular Transport Proteins

Source

Identifiers

PMID: 23536430
DOI: 10.1002/mds.25430

Genes

VPS35

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The VPS35 gene and Parkinson's disease.PMID 23536430Read ↗

VPS35, the Retromer Complex and Parkinson's Disease.Semantic proximity Read ↗

Deciphering the role of VPS35 in Parkinson's diseaseSemantic proximity Read ↗

VPS35 mutations in Parkinson disease.Semantic proximity Read ↗

VPS35, the core component of the retromer complex, and Parkinson's diseaseSemantic proximity Read ↗

VPS35 and the mitochondria: Connecting the dots in Parkinson's disease pathophysiologySemantic proximity Read ↗

The Role of VPS35 in the Pathobiology of Parkinson’s DiseaseSemantic proximity Read ↗

Parkinson's disease–associated mutant VPS35 causes mitochondrial dysfunction by recycling DLP1 complexesSemantic proximity Read ↗

The VPS35 protein and the role of its impairments in mitochondrial dysfunction in Parkinson's disease.Semantic proximity Read ↗

VPS35 Deficiency or Mutation Causes Dopaminergic Neuronal Loss by Impairing Mitochondrial Fusion and FunctionSemantic proximity Read ↗

Parkinson's disease-linked mutations in VPS35 induce dopaminergic neurodegeneration.Semantic proximity Read ↗

VPS35 and retromer dysfunction in Parkinson's disease.Semantic proximity Read ↗

Parkinson's disease-associated pathogenic VPS35 mutation causes complex I deficitsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.