Article
Infected dendritic cells facilitate systemic dissemination and transplacental passage of the obligate intracellular parasite Neospora caninum in mice.
PloS one - 1 Jan 2012
Collantes-Fernandez Esther, Arrighi Romanico B G, Alvarez-García Gema, Weidner Jessica M, Regidor-Cerrillo Javier, Boothroyd John C, Ortega-Mora Luis M, Barragan Antonio
Abstract excerpt
The obligate intracellular parasite Neospora caninum disseminates across the placenta and the blood-brain barrier, to reach sites where it causes severe pathology or establishes chronic persistent infections. The mechanisms used by N. caninum to breach restrictive biological barriers remain elusive. To examine the cellular basis of these processes, migration of different N. caninum isolates (Nc-1, Nc-Liverpool,...
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