Article
Haplotype variation, recombination, and gene conversion within the turkey MHC-B locus.
Immunogenetics - 1 Jul 2010
Chaves Lee D, Faile Gretchen M, Krueth Stacy B, Hendrickson Julie A, Reed Kent M
Abstract excerpt
The major histocompatibility complex (MHC) is a gene dense region with profound effects on the disease phenotype. In many species, characterizations of MHC polymorphisms have focused on identifying allelic haplotypes of the highly polymorphic class I and class II loci through direct immunological approaches such as monoclonal antibodies specific for the major antigens or indirectly through DNA sequence-based...
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