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Article

Influence of the CYP2B6 polymorphism on the pharmacokinetics of mitotane.

Pharmacogenetics and genomics - 1 Jun 2013

D'Avolio Antonio, De Francia Silvia, Basile Vittoria, Cusato Jessica, De Martino Francesca, Pirro Elisa, Piccione Francesca, Ardito Arianna, Zaggia Barbara, Volante Marco, Di Perri Giovanni, Terzolo Massimo

Abstract excerpt

OBJECTIVE: The aim of this study was to assess the potential impact of the pharmacogenetic variability of CYP2B6 and ABCB1 genes on the pharmacokinetics of mitotane. METHODS: A retrospective analysis was carried out on 27 patients with adrenocortical carcinoma on postoperative adjunctive mitotane...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ATP Binding Cassette Transporter, Subfamily B

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Source

Identifiers

PMID: 23524664
DOI: 10.1097/FPC.0b013e3283606cb2

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23524664-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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