Article
Rapid and Complete Remission of Metastatic Adrenocortical Carcinoma Persisting 10 Years After Treatment With Mitotane Monotherapy: Case Report and Review of the Literature.
Medicine - 1 Mar 2016
El Ghorayeb Nada, Rondeau Geneviève, Latour Mathieu, Cohade Christian, Olney Harold, Lacroix André, Perrotte Paul, Sabourin Alexis, Mazzuco Tania L, Bourdeau Isabelle
Abstract excerpt
Mitotane has been used for more than 5 decades as therapy for adrenocortical carcinoma (ACC). However its mechanism of action and the extent of tumor response remain incompletely understood. To date no cases of rapid and complete remission of metastatic ACC with mitotane monotherapy has been reported. A 52-year-old French Canadian man presented with metastatic disease 2 years following a right adrenalectomy for...
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