Article
CD98 marks a subpopulation of head and neck squamous cell carcinoma cells with stem cell properties
19 Feb 2013
Abstract excerpt
Patients with advanced head and neck squamous cell carcinomas (HNSCCs) are often treated with concomitant chemotherapy and radiotherapy, but only 50% is cured. A possible explanation for treatment failure is therapy resistance of the cancer stem cells (CSCs). The application of compounds specifically targeting these CSCs, in addition to routinely used therapeutics, would likely improve clinical outcome. We...
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