Article
Unraveling the brain regulation of appetite: lessons from genetics.
Nature neuroscience - 1 Oct 2012
Yeo Giles S H, Heisler Lora K
Abstract excerpt
Over the past 20 years, genetic studies have illuminated critical pathways in the hypothalamus and brainstem mediating energy homeostasis, such as the melanocortin, leptin, 5-hydroxytryptamine and brain-derived neurotrophic factor signaling axes. The identification of these pathways necessary for appropriate appetitive responses to energy state has yielded insight into normal homeostatic processes. Although...
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