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Immunomodulatory activities of surface-layer proteins obtained from epidemic and hypervirulent Clostridium difficile strains

25 Feb 2011

Abstract excerpt

Surface-layer proteins (SLPs) have been detected in all Clostridium difficile strains and play a role in adhesion, although an involvement in the inflammatory process may also be supposed, as they cover the bacterial surface and are immunodominant antigens. The aim of this study was to evaluate the immunomodulatory properties of SLPs obtained from hypervirulent and epidemic (H/E) or non-H/E C. difficile strains,...

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PMID: 21349985
DOI: 10.1099/jmm.0.029694-0

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