Development of an attenuated potato virus Y mutant carrying multiple mutations in helper-component protease for cross-protection.

doi:10.1016/j.virusres.2024.199369

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Article

Development of an attenuated potato virus Y mutant carrying multiple mutations in helper-component protease for cross-protection.

Virus research - 1 Jun 2024

Xu Xiao-Jie, Sun Xu-Jie, Liu Chun-Ju, Chen Xiu-Zhai, Zhu Qing, Tian Yan-Ping, Li Xiang-Dong

Abstract excerpt

Tobacco (Nicotiana tabacum) is one of the major cash crops in China. Potato virus Y (PVY), a representative member of the genus Potyvirus, greatly reduces the quality and yield of tobacco leaves by inducing veinal necrosis. Mild strain-mediated cross-protection is an attractive method of controlling diseases caused by PVY. Currently, there is a lack of effective and stable attenuated PVY mutants. Potyviral helper...

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PMID: 38608732
DOI: 10.1016/j.virusres.2024.199369
PMCID: PMC11035042

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