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Article

Structural characterization of HC-Pro, a plant virus multifunctional protein.

The Journal of biological chemistry - 27 Jun 2003

Plisson Célia, Drucker Martin, Blanc Stéphane, German-Retana Sylvie, Le Gall Olivier, Thomas Daniel, Bron Patrick

Abstract excerpt

The helper component proteinase (HC-Pro) is a key protein encoded by plant viruses of the genus Potyvirus. HC-Pro is involved in different steps of the viral cycle, aphid transmission, replication, and virus cell-to-cell and systemic movement and is a suppressor of post-transcriptional gene silencing. Structural knowledge of HC-Pro is required to better understand its multiple functions. To this aim, we purified...

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PMID: 12684502
DOI: 10.1074/jbc.M302512200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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