Article
Canine DLA-79 gene: an improved typing method, identification of new alleles and its role in graft rejection and graft-versus-host disease.
Tissue antigens - 1 Apr 2013
Venkataraman G M, Geraghty D, Fox J, Graves S S, Zellmer E, Storer B E, Torok-Storb B J, Storb R
Abstract excerpt
Developing a preclinical canine model that predicts outcomes for hematopoietic cell transplantation in humans requires a model that mimics the degree of matching between human donor and recipient major histocompatibility complex (MHC) genes. The polymorphic class I and class II genes in mammals are typically located in a single chromosome as part of the MHC complex. However, a divergent class I gene in dogs,...
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