Article
α-Lipoic acid-induced inhibition of proliferation and met phosphorylation in human non-small cell lung cancer cells.
Cancer letters - 28 Jul 2013
Michikoshi Hiromitsu, Nakamura Takahiro, Sakai Katsuya, Suzuki Yoshinori, Adachi Eri, Matsugo Seiichi, Matsumoto Kunio
Abstract excerpt
α-Lipoic acid (α-LA), a naturally occurring anti-oxidant and co-factor for metabolic enzymes, suppresses the growth of different types of tumor cells. The mechanisms that are responsible for these results, however, remain to be elucidated. In the present study, we investigated the effects of α-LA on the proliferation and activation status of definitive receptor tyrosine kinases, epidermal growth factor receptor...
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