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Selective Growth Inhibition of Human Leukemia and Human Lymphoblastoid Cells by Resveratrol via Cell Cycle Arrest and Apoptosis Induction

26 Jul 2008

Abstract excerpt

There is great interest in the potential chemopreventive activity of resveratrol against human cancers. However, there are conflicting results on its growth inhibitory effect on normal cells. This project examined the differential effect of resveratrol at physiologically relevant concentrations on nonmalignant (WIL2-NS) and malignant (HL-60) cell lines and compared the underlying mechanisms via cell cycle...

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PMID: 18656932
DOI: 10.1021/jf801014p

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