Article
Effects of coexisting polymorphisms of CYP2C19 and P2Y12 on clopidogrel responsiveness and clinical outcome in patients with acute coronary syndromes undergoing stent-based coronary intervention.
Chinese medical journal - 1 Mar 2013
Tang Xiao-Fang, Zhang Jia-Hui, Wang Jing, Han Ya-Ling, Xu Bo, Qiao Shu-Bin, Wu Yong-Jian, Chen Jue, Wu Yuan, Chen Ji-Lin, Gao Run-Lin, Yang Yue-Jin, Yuan Jin-Qing
Abstract excerpt
BACKGROUND: The CYP2C19 G681A single polymorphism has been proven to affect clopidogrel responsiveness. However, the effect of coexisting polymorphisms of other genes has not yet been reported in the Chinese population. This study investigated the effect of coexisting polymorphisms of CYP2C19 and...
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