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Article

First-degree relatives of patients with rheumatoid arthritis exhibit high prevalence of joint symptoms.

The Journal of rheumatology - 1 Jun 2013

Smolik Irene, Robinson David B, Bernstein Charles N, El-Gabalawy Hani S

Abstract excerpt

OBJECTIVE: The preclinical period of rheumatoid arthritis (RA) is characterized by the presence of autoantibodies such as anticitrullinated protein antibodies (ACPA) and rheumatoid factor (RF). Little is known about the joint symptom profile preceding onset of RA, and whether symptoms are associated with RA autoantibodies. Because first-degree relatives (FDR) of North American Native (NAN) RA probands exhibit...

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Identifiers

PMID: 23504380
DOI: 10.3899/jrheum.121016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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