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Article

Mapping global effects of the anti-sigma factor MucA in Pseudomonas fluorescens SBW25 through genome-scale metabolic modeling.

BMC systems biology - 11 Mar 2013

Borgos Sven E F, Bordel Sergio, Sletta Håvard, Ertesvåg Helga, Jakobsen Øyvind, Bruheim Per, Ellingsen Trond E, Nielsen Jens, Valla Svein

Abstract excerpt

BACKGROUND: Alginate is an industrially important polysaccharide, currently produced commercially by harvesting of marine brown sea-weeds. The polymer is also synthesized as an exo-polysaccharide by bacteria belonging to the genera Pseudomonas and Azotobacter, and these organisms may represent an alternative alginate source in the future. The current work describes an attempt to rationally develop a biological...

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Identifiers

PMID: 23497367
DOI: 10.1186/1752-0509-7-19
PMCID: PMC3641028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Mapping global effects of the anti-sigma factor MucA in Pseudomonas fluorescens SBW25 through genome-scale metabolic modeling.PMID 23497367Read ↗

Fluxome study of Pseudomonas fluorescens reveals major reorganisation of carbon flux through central metabolic pathways in response to inactivation of the anti-sigma factor MucA.Semantic proximity Read ↗

Identification of genes affecting alginate biosynthesis in Pseudomonas fluorescens by screening a transposon insertion library.Semantic proximity Read ↗

Metabolic profiling of Pseudomonas aeruginosa demonstrates that the anti-sigma factor MucA modulates osmotic stress tolerance.Semantic proximity Read ↗

Evidence for Sigma Factor Competition in the Regulation of Alginate Production by Pseudomonas aeruginosaSemantic proximity Read ↗

Characterization of the genes coding for the putative sigma factor AlgU and its regulators MucA, MucB, MucC, and MucD in Azotobacter vinelandii and evaluation of their roles in alginate biosynthesis.Semantic proximity Read ↗

Mutations in the mucA gene of Pseudomonas aeruginosa promote disease exacerbation.Semantic proximity Read ↗

MucA-mediated coordination of type III secretion and alginate synthesis in Pseudomonas aeruginosa.Semantic proximity Read ↗

Expression of mucoid induction factor MucE is dependent upon the alternate sigma factor AlgU in Pseudomonas aeruginosaSemantic proximity Read ↗

Alginate Polymerization and Modification Are Linked in Pseudomonas aeruginosa.Semantic proximity Read ↗

Identification of algF in the alginate biosynthetic gene cluster of Pseudomonas aeruginosa which is required for alginate acetylation.Semantic proximity Read ↗

The Pseudomonas aeruginosa homeostasis enzyme AlgL clears the periplasmic space of accumulated alginate during polymer biosynthesisSemantic proximity Read ↗

Outer-membrane protein LptD (PA0595) plays a role in the regulation of alginate synthesis in Pseudomonas aeruginosa.Semantic proximity Read ↗

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