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Article

Investigation of epistasis between DAOA and 5HTR1A variants on clinical outcomes in patients with schizophrenia.

Genetic testing and molecular biomarkers - 1 Jun 2013

Chiesa Alberto, Lia Loredana, Han Changsu, Lee Soo-Jung, Pae Chi-Un, Serretti Alessandro

Abstract excerpt

PURPOSE: In two recent studies of our group, rs10042486, a single-nucleotide polymorphism (SNP) within 5HTR1A, and rs7139958, a SNP within the d-amino acid oxidase activator (DAOA) were found to be associated with clinical improvement, as detected by the positive symptom subscale of the Positive and Negative Symptoms Scale (PANSS) in a sample 221 Korean schizophrenia patients treated with various antipsychotics....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Asian People
Share to Carrier Proteins
Share to Epistasis, Genetic
Share to Genetic Variation
Share to Intracellular Signaling Peptides and Proteins
Share to Polymorphism, Single Nucleotide
Share to Receptor, Serotonin, 5-HT1A
Share to Schizophrenia

Source

Identifiers

PMID: 23495896
DOI: 10.1089/gtmb.2012.0484

Genes

DAOA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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